Two new triterpenes cycloartane-type, 1.1x1.5 named 24-methylencycloartan-12-oxo-3β,22α-diol and trichiliol, were isolated from the leaves of Trichilia casaretti C.DC.together with three known triterpenes—24-methylencycloart-3β,22-diol, 22,25-dihydrocycloart-23(E)-en-3β-ol, and 22(R)-hydroxycycloart-24-en-3-ol.These compo
Abstract Background: Early administration of antibiotics in sepsis is associated with improved patient outcomes, but safe and generalizable approaches to de-escalate or discontinue antibiotics after suspected sepsis events are unknown.Methods: We used a modified Delphi approach to identify safety criteria for an opt-out protocol to guide de-escalat
Norepinephrine superhero lollipops (NE) is often administered during the perioperative period of liver transplantation to address hemodynamic instability and to improve organ perfusion and oxygen supply.However, its role and safety profile have yet to be evaluated in pediatric living donor liver transplantation (LDLT).We hypothesized that intraoper
The Caribbean reef shark (Carcharhinus perezi; Poey, 1876) is a medium to large-bodied coastal and reef-associated predator found throughout the subtropical and tropical waters of the Atlantic Ocean and Caribbean Sea, although its populations are increasingly saxemodel threatened by overfishing.We describe the first mitochondrial genome sequence fo
In recent years, underwater shield moonbon tunnels are being developed according to large-scale sections.The problems of large buried depth and high water pressure have posed major challenges to the safety of segmented structures.The load-bearing capacity and damage of segmented structures under high water pressure features have always attracted at